Wednesday, May 2, 2018
Workshop 1: One Medicine One Science Approaches to Human Health
at Two NIH Institutes
Coordinators: Hortencia Hornbeak, Peter Jackson, Kimberly Thigpen Tart, Heather Henry
National Institutes of Health (NIAID, and NIEHS – Joint)
This workshop will explore One Medicine One Science (OMOS) approaches applied at two NIH institutes to complex human health issues requiring coordinated, multi-disciplinary research programs and teams. Senior institute staff and funded investigators of the National Institute of Allergy and Infectious Disease (NIAID) and the National Institute of Environmental Health Sciences (NIEHS) will lead discussions of (a) Zika as a case study of an emerging disease and pandemic threat, and (b) studies of chronic disease resulting from the interactions of living systems with environmental threats such as chemicals and other contaminants that affect human health. Presentations will feature diverse NIH-supported OMOS-related research studies and will discuss methods and resources for integrating OMOS approaches into aspects of infectious disease and environmental research including surveillance, epidemiology, prevention and intervention, data collection and analysis, partnership building, and training and capacity building.
Workshop 2: Effective Policy when Consumer Preferences Do Not Match Actions
Coordinators: Shaun Kennedy, Amy McMillen University of Minnesota;
Markus Lipp, Food and Agricultural Organization of the United Nations
The public in general or a significant subset often drive specific food and health policies as governments and the private sector attempt to meet their expressed desires. The challenge for effective policy implementation, however, is that consumers do not always choose health behaviors or foods that are consistent with their priorities. This is especially challenging when consumers make choices based on one priority that appears to conflict with other expressed priorities. While not a new concept in philosophy or what is sometimes called moral mathematics, it is not generally applied when developing and implementing health and food policies. This is easy to understand when it is an economic priority, cost, overriding a personal priority, enhanced food safety, with simple choices such as not purchasing irradiated ground beef for food safety due to the cost of irradiation. It becomes far more complicated to implement effective policy when it is more nuanced such as consumers making health or food choices that are demonstrably less favorable to their own family’s health or the environment than alternatives. This workshop will look at how to consider health or food policies in the face of competitive, unexpressed or conflicting priorities and the extent to which the policies can achieve their objectives. It will draw beyond policy experts to include experts in consumer behavior, individual to group dynamics, game theory and economics from the academic, public and private sectors to consider policy differently.
Workshop 3: Breaking Silos and Building Bridges Within and Across Geographies for One Medicine One Science Policy
Coordinators: Andres Perez, Arda Sancak
University of Minnesota, Turkish Public Health Institute
Despite an increasingly popular One Health rhetoric, authentic examples of multiple disciplinary efforts to transcend the traditional silos of public, animal, and environmental health are still rare. A number of organizations across regions worldwide have agreed to collaborate on research and outreach activities on One Health and policy. The group is collectively referred to as Consortium for One Medicine, One Science (COMOS). The ultimate goal of COMOS is to contribute to securing food and protecting health of human, animals, and the environment through a network of equal partners within and between regions. Integral and cross-cutting to the disciplinary areas of focus is the importance of effective policy and program development and implementation. We will utilize various policy-focused frameworks and tools to ensure that our collective work influences policy design, and our research outputs and outcomes inform strategic programmatic development. By incorporating policy tools and frameworks, we are connecting our research outputs to operational capacity in aspiration of having lasting impact on how and why we collaborate to manage dynamic grand challenges at the interface of humans, animals, and the environment. In this workshop, a summary of research and outreach activities in Ibero-America, South East Asia, and Turkey, planned and conducted under the COMOS umbrella, will be presented, discussed, and evaluated.
Workshop 4: Precision Medicine and Genome Editing: Science and Ethics
Coordinators: Cliff Steer, Pamala Jacobson, University of Minnesota, and Kavita Berger, Gryphon Scientific
According to the NIH, precision medicine is "an emerging approach for disease treatment and prevention that takes into account individual variability in genes, environment, and lifestyle for each person." It refers to the tailoring of medical treatment to the individual characteristics of each patient and the ability to classify individuals into subpopulations that differ in the biology, susceptibility and response to treatment for a particular disease. In January 2015, the US President launched the Precision Medicine Initiative (PMI), a bold new research effort to revolutionize how we improve health and treat disease, empowering health care providers to tailor treatment and prevention strategies to individuals’ unique characteristics. Gene editing uses engineered nucleases or so-called “molecular scissors” to make changes to specific DNA sequences in the genome of a living organism. They include meganucleases, zinc finger nucleases (ZFNs), transcription activator-like effector-based nucleases (TALENs), and the clustered regularly interspaced short palindromic repeats (CRISPR)-Cas system. Genome editing is being developed to treat not only genetic diseases but also infectious diseases and those that have both a genetic and an environmental component. It is now widely used in biomedical research, including creation of disease models with desired genetic mutations, screening in a high-throughput manner for drug resistance genes, and making appropriate editions to genes in vivo for disease treatment. All of these applications have been facilitating the development of precision medicine research.
Workshop 5: Science Communication and Strategic Engagement of Policy Makers
Coordinators: American Association of Advancement of Science (AAAS)
Science Communication will help scientists develop their public communication and outreach skills. Effective scientist-communicators who foster information-sharing and respect between science and the public are essential for true public communication of and engagement with science. Scientists are increasingly requested by their institutions and funding agencies to extend beyond the scientific community and communicate their research directly to public audiences, but traditional scientific training typically does not prepare scientists to be effective public communicators. However, there currently are too few effective emissaries for science. Communication is typically an acquired, not an innate skill.
Strategic Engagement of Policy Makers will provide guidance in navigating engagements with key decision makers. Participants will discuss successful methods within an ever-changing landscape. It will include facilitator presentations and attendee exercises.